The database is currently under construction.
   
 
 
 
 

PUBLICATIONS RELEVANT TO BRAINSTEM GENETICS RESEARCH

(use PubMed to obtain complete publication lists for the group leaders)

 

2005

Grillet N, Pattyn A, Contet C, Kieffer BL, Goridis C, Brunet JF. (2005) Generation and characterization of Rgs4 mutant mice. Mol Cell Biol. 25:4221-4228.


Durand E, Dauger S, Pattyn A, Gaultier C, Goridis C, Gallego J. (2005) Sleep-disordered breathing in newborn mice heterozygous for the transcription factor Phox2b. Am J Respir Crit Care Med. 172:238-243.


Huber K, Karch N, Ernsberger U, Goridis C, Unsicker K. (2005) The role of Phox2B in chromaffin cell development. Dev Biol. 279:501-508.


Murakami Y, Uchida K, Rijli FM, Kuratani S. (2005) Evolution of the brain developmental plan: Insights from agnathans. Dev Biol. 280:249-259.


Henseleit KD, Nelson SB, Kuhlbrodt K, Hennings JC, Ericson J, Sander M. (2005) NKX6 transcription factor activity is required for (alpha)- and (beta)-cell development in the pancreas. Development. 132:3139-3149.


Singh MK, Christoffels VM, Dias JM, Trowe MO, Petry M, Schuster-Gossler K, Burger A, Ericson J, Kispert A. (2005) Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2. Development. 132:2697-2707.


Vallstedt A, Klos JM, Ericson J. (2005) Multiple dorsoventral origins of oligodendrocyte generation in the spinal cord and hindbrain. Neuron. 45:55-67.


Pascual O, Traiffort E, Baker DP, Galdes A, Ruat M, Champagnat J. (2005) Sonic hedgehog signalling in neurons of adult ventrolateral nucleus tractus solitarius. Eur J Neurosci. 22:389-396.


Thoby-Brisson M, Trinh JB, Champagnat J, Fortin G. (2005) Emergence of the pre-Botzinger respiratory rhythm generator in the mouse embryo. J Neurosci. 25:4307-4318.


Silva-Barrat C, Velluti J, Szente M, Batini C, Champagnat J. (2005) Exaggeration of epileptic-like patterns by nicotine receptor activation during the GABA withdrawal syndrome. Brain Res. 1042:133-143.


Michel FJ, Fortin GD, Martel P, Yeomans J, Trudeau LE. (2005) M3-like muscarinic receptors mediate Ca2+ influx in rat mesencephalic GABAergic neurones through a protein kinase C-dependent mechanism. Neuropharmacology. 48:796-809.


Boudinot E, Taysse L, Daulon S, Chatonnet A, Champagnat J, Foutz AS. (2005) Effects of acetylcholinesterase and butyrylcholinesterase inhibition on breathing in mice adapted or not to reduced acetylcholinesterase. Pharmacol Biochem Behav. 80:53-61.


Vernay B, Koch M, Vaccarino F, Briscoe J, Simeone A, Kageyama R, Ang SL. (2005) Otx2 regulates subtype specification and neurogenesis in the midbrain. J Neurosci. 25:4856-4867.


Gotz K, Briscoe J, Ruther U. (2005) Homozygous Ft embryos are affected in floor plate maintenance and ventral neural tube patterning. Dev Dyn. 233:623-630.


Stamataki D, Ulloa F, Tsoni SV, Mynett A, Briscoe J. (2005) A gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tube. Genes Dev. 19:626-641.


Placzek M, Briscoe J. (2005) The floor plate: multiple cells, multiple signals. Nat Rev Neurosci. 6:230-240.


Briscoe J, Therond P. (2005) Hedgehog signaling: from the Drosophila cuticle to anti-cancer drugs. Dev Cell. 8:143-151.


Cheung M, Chaboissier MC, Mynett A, Hirst E, Schedl A, Briscoe J. (2005) The transcriptional control of trunk neural crest induction, survival, and delamination. Dev Cell. 8:179-192.


Sigurjonsson OE, Perreault MC, Egeland T, Glover JC. (2005) Adult human hematopoietic stem cells produce neurons efficiently in the regenerating chicken embryo spinal cord. Proc Natl Acad Sci U S A. 102:5227-5232.


Fjeldheim AK, Hovring PI, Loseth OP, Johansen PW, Glover JC, Matre V, Olstad OK, Reppe S, Gordeladze JO, Walaas SI, Gautvik KM. (2005) Thyrotrophin-releasing hormone receptor 1 and prothyrotrophin-releasing hormone mRNA expression in the central nervous system are regulated by suckling in lactating rats. Eur J Endocrinol. 152:791-803.


Nissen UV, Mochida H, Glover JC. (2005) Development of projection-specific interneurons and projection neurons in the embryonic mouse and rat spinal cord. J Comp Neurol. 483:30-47.

 

2004

Samad OA, Geisen MJ, Caronia G, Varlet I, Zappavigna V, Ericson J, Goridis C, Rijli FM. (2004) Integration of anteroposterior and dorsoventral regulation of Phox2b transcription in cranial motoneuron progenitors by homeodomain proteins. Development. 131:4071-4083.


Pattyn A, Simplicio N, van Doorninck JH, Goridis C, Guillemot F, Brunet JF. (2004) Ascl1/Mash1 is required for the development of central serotonergic neurons. Nat Neurosci. 7:589-595.


Tsarovina K, Pattyn A, Stubbusch J, Muller F, van der Wees J, Schneider C, Brunet JF, Rohrer H. (2004) Essential role of Gata transcription factors in sympathetic neuron development. Development. 2004 131:4775-4786.


Cross SH, Morgan JE, Pattyn A, West K, McKie L, Hart A, Thaung C, Brunet JF, Jackson IJ. (2004) Haploinsufficiency for Phox2b in mice causes dilated pupils and atrophy of the ciliary ganglion: mechanistic insights into human congenital central hypoventilation syndrome. Hum Mol Genet. 13:1433-1439.


Takio Y, Pasqualetti M, Kuraku S, Hirano S, Rijli FM, Kuratani S. Evolutionary biology: lamprey Hox genes and the evolution of jaws. Nature. 429:1 p following 262.


Murakami Y, Pasqualetti M, Takio Y, Hirano S, Rijli FM, Kuratani S. Segmental development of reticulospinal and branchiomotor neurons in lamprey: insights into the evolution of the vertebrate hindbrain. Development. 131:983-995.


Sandelin A, Bailey P, Bruce S, Engstrom PG, Klos JM, Wasserman WW, Ericson J, Lenhard B. (2004) Arrays of ultraconserved non-coding regions span the loci of key developmental genes in vertebrate genomes. BMC Genomics. 5:99.


Chatonnet F, Boudinot E, Chatonnet A, Champagnat J, Foutz AS. (2004) Breathing without acetylcholinesterase. Adv Exp Med Biol. 551:165-170.


Fortin G, Borday C, Germon I, Champagnat J. (2004) Breathing at birth: influence of early developmental events. Adv Exp Med Biol. 551:143-148.


Thoby-Brisson M, Autran S, Fortin G, Champagnat J. (2004) BDNF preferentially targets membrane properties of rhythmically active neurons in the pre-Botzinger complex in neonatal mice. Adv Exp Med Biol. 551:115-120.


Coutinho AP, Borday C, Gilthorpe J, Jungbluth S, Champagnat J, Lumsden A, Fortin G. (2004) Induction of a parafacial rhythm generator by rhombomere 3 in the chick embryo. J Neurosci. 24:9383-9390.


Boudinot E, Emery MJ, Mouisel E, Chatonnet A, Champagnat J, Escourrou P, Foutz AS. (2004) Increased ventilation and CO2 chemosensitivity in acetylcholinesterase knockout mice. Respir Physiol Neurobiol. 140:231-241.


Boudinot E, Yamada M, Wess J, Champagnat J, Foutz AS. (2004) Ventilatory pattern and chemosensitivity in M1 and M3 muscarinic receptor knockout mice. Respir Physiol Neurobiol. 139:237-245.


Borday C, Wrobel L, Fortin G, Champagnat J, Thaeron-Antono C, Thoby-Brisson M. (2004) Developmental gene control of brainstem function: views from the embryo. Prog Biophys Mol Biol. 84:89-106.


Briscoe J. (2004) Hedgehog signaling: measuring ligand concentrations with receptor ratios. Curr Biol. 14:R889-891.


Price SR, Briscoe J. (2004) The generation and diversification of spinal motor neurons: signals and responses. Mech Dev. 2004 121:1103-1115.


Briscoe J, Wilkinson DG. (2004) Establishing neuronal circuitry: Hox genes make the connection. Genes Dev. 18:1643-1648.

 


2003

Dauger S, Pattyn A, Lofaso F, Gaultier C, Goridis C, Gallego J, Brunet JF. (2003) Phox2b controls the development of peripheral chemoreceptors and afferent visceral pathways. Development. 130:6635-6642.


Grillet N, Dubreuil V, Dufour HD, Brunet JF. (2003) Dynamic expression of RGS4 in the developing nervous system and regulation by the neural type-specific transcription factor Phox2b. J Neurosci. 23:10613-10621.


Cheung M, Briscoe J. (2003) Neural crest development is regulated by the transcription factor Sox9. Development. 130:5681-5693.


Jacob J, Briscoe J. (2003) Gli proteins and the control of spinal-cord patterning. EMBO Rep. 4:761-765.

Santagati F, Rijli FM (2003) Cranial neural crest and the building of the vertebrate head. Nature Review Neuroscience 4:806-818.

Pattyn A, Vallstedt A, Dias JM, Samad OA, Krumlauf R, Rijli FM, Brunet JF, Ericson J. (2003) Coordinated temporal and spatial control of motor neuron and serotonergic neuron generation from a common pool of CNS progenitors. Genes Dev. 17:729-737.

Diaz C, Glover JC, Puelles L, Bjaalie JG. (2003) The relationship between hodological and cytoarchitectonic organization in the vestibular complex of the 11-day chicken embryo. J Comp Neurol. 457:87-105.

Fortin G, Charnay P, Champagnat J. (2003) Linking respiratory rhythm generation to segmentation of the vertebrate hindbrain.
Pflugers Arch. 446:514-515.

Glover, JC (2003) The vestibular system. In: Encyclopedia of Neuroscience; G Adelman, BH Smith, editors; Elsevier.

Glover, JC (2003) The development of vestibulo-ocular circuitry in the chicken embryo. J Physiol (Paris) 97:17-25.

Pattyn A, Vallsted A, Dias J, Sander M and Ericson J (2003). Complementary roles for Nkx6 and Nkx2 class proteins in the establishment of motor neuron identity in the hindbrain. Development,130:4149-4159.

Ding Y-Q, Marklund U, Yuan W, Yin J, Wegman L, Ericson J, Deneris E, Johnson RL and Chen ZF (2003) Lmx1b is essential for the development of serotonergic neurons. Nat. Neurosci. 6:933-938.

Borday C, Abadie V, Chatonnet F, Thoby-Brisson M, Champagnat J, Fortin G (2003) Developmental molecular switches regulating breathing patterns in CNS. Respir Physiol. Neurobiol., 135:121-132.

Chatonnet F, Domínguez del Toro E, Thoby-Brisson M, Champagnat J, Fortin G, Rijli FM and Thaëron-Antôno C (2003) From hindbrain segmentation to breathing after birth: developmental patterning in rhombomeres 3 and 4. Mol Neurobiol. 28:277-294.

Tiveron M-C, Pattyn A, Hirsch M-R and Brunet J-F (2003) Role of Phox2b and Mash1 in the generation of the vestibular efferent nucleus, Develop. Biol.260:46-57.


2002

Dubreuil V, Hirsch MR, Jouve C, Brunet JF, Goridis C. (2002) The role of Phox2b in synchronizing pan-neuronal and type-specific aspects of neurogenesis. Development. 129(22):5241-53.

Goridis C, Rohrer H. (2002) Specification of catecholaminergic and serotonergic neurons. Nat Rev Neurosci. 3(7):531-41. Review.

Brunet JF, Pattyn A. (2002) Phox2 genes - from patterning to connectivity. Curr Opin Genet Dev. 12(4):435-40.

Diaz C, Glover JC. (2002) Comparative aspects of the hodological organization of the vestibular nuclear complex and related neuron populations. Brain Res Bull. 57(3-4):307-12.

Persson M, Stamataki D, te Welscher P, Andersson E, Bose J, Ruther U, Ericson J, Briscoe J. (2002) Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity. Genes Dev. 16(22):2865-78.

Ren SY, Angrand PO, Rijli FM. (2002) Targeted insertion results in a rhombomere 2-specific Hoxa2 knockdown and ectopic activation of Hoxa1 expression. Dev Dyn. 225(3):305-15.

Pasqualetti M, Rijli FM. (2002) Developmental biology: the plastic face.
Nature. 416(6880):493-4.

Pasqualetti M, Ren SY, Poulet M, LeMeur M, Dierich A, Rijli FM. (2002) A Hoxa2 knockin allele that expresses EGFP upon conditional Cre-mediated recombination.Genesis. 32(2):109-11.

Ren SY, Pasqualetti M, Dierich A, Le Meur M, Rijli FM. (2002) A Hoxa2 mutant conditional allele generated by Flp- and Cre-mediated recombination. Genesis. 32(2):105-8.

Chatonnet F, Thoby-Brisson M, Abadie V, Dominguez del Toro E, Champagnat J, Fortin G. (2002) Early development of respiratory rhythm generation in mouse and chick.Respir Physiolo Neurobiol. 131(1-2):5-13.

Boudinot E, Tremblay P, Champagnat J, Foutz AS. (2002) Respiratory function in mice lacking or overexpressing the prion protein.Neurosci Lett. 323(2):89-92.

Jungbluth S, Willecke K, Champagnat J. (2002) Segment-specific expression of connexin31 in the embryonic hindbrain is regulated by Krox20.Dev Dyn 223(4):544-51.

Chatonnet F, del Toro ED, Voiculescu O, Charnay P, Champagnat J. (2002) Different respiratory control systems are affected in homozygous and heterozygous kreisler mutant mice.Eur J Neurosci. 15(4):684-92.


2001

Flora A, Lucchetti H, Benfante R, Goridis C, Clementi F, Fornasari D. (2001) Sp proteins and Phox2b regulate the expression of the human Phox2a gene. J Neurosci. 21(18):7037-45.

Glover JC. (2001) Correlated patterns of neuron differentiation and Hox gene expression in the hindbrain: a comparative analysis. Brain Res Bull. 55(6):683-93.

Vincent JP, Briscoe J. (2001) Morphogens. Curr Biol. 11(21):R851-4.

Briscoe J, Chen Y, Jessell TM, Struhl G. (2001) A hedgehog-insensitive form of patched provides evidence for direct long-range morphogen activity of sonic hedgehog in the neural tube. Mol Cell. 7(6):1279-91.

Briscoe J, Ericson J. (2001) Specification of neuronal fates in the ventral neural tube. Curr Opin Neurobiol. 11(1):43-9.

Wallen A A, Castro DS, Zetterstrom RH, Karlen M, Olson L, Ericson J, Perlmann T. (2001) Orphan nuclear receptor Nurr1 is essential for Ret expression in midbrain dopamine neurons and in the brain stem. Mol Cell Neurosci. 18(6):649-63.

Vallstedt A, Muhr J, Pattyn A, Pierani A, Mendelsohn M, Sander M, Jessell TM, Ericson J. (2001) Different levels of repressor activity assign redundant and specific roles to Nkx6 genes in motor neuron and interneuron specification. Neuron. 31(5):743-55.

Muhr J, Andersson E, Persson M, Jessell TM, Ericson J. (2001) Groucho-mediated transcriptional repression establishes progenitor cell pattern and neuronal fate in the ventral neural tube. Cell. 104(6):861-73.

Pasqualetti M, Neun R, Davenne M, Rijli FM. (2001) Retinoic acid rescues inner ear defects in Hoxa1 deficient mice. Nat Genet. 29(1):34-9.

del Toro ED, Borday V, Davenne M, Neun R, Rijli FM, Champagnat J. (2001) Generation of a novel functional neuronal circuit in Hoxa1 mutant mice. J Neurosci. 21(15):5637-42.

Pasqualetti M, Rijli FM. (2001) Homeobox gene mutations and brain-stem developmental disorders: learning from knockout mice.
Curr Opin Neurol. 14(2):177-84.


2000

Dubreuil V, Hirsch MR, Pattyn A, Brunet JF, Goridis C. (2000) The Phox2b transcription factor coordinately regulates neuronal cell cycle exit and identity. Development. 127(23):5191-201.

Pattyn A, Goridis C, Brunet JF. (2000) Specification of the central noradrenergic phenotype by the homeobox gene Phox2b. Mol Cell Neurosci. 15(3):235-43.

Pattyn A, Hirsch M, Goridis C, Brunet JF. (2000) Control of hindbrain motor neuron differentiation by the homeobox gene Phox2b. Development. 127(7):1349-58.

Glover JC. (2000) Neuroepithelial 'compartments' and the specification of vestibular projections. Prog Brain Res. 124:3-21.

Glover JC. (2000) Development of specific connectivity between premotor neurons and motoneurons in the brain stem and spinal cord. Physiol Rev. 80(2):615-47.

Hoover F, Kielland A, Glover JC. (2000) RXR gamma gene is expressed by discrete cell columns within the alar plate of the brainstem of the chicken embryo. J Comp Neurol. 416(4):417-28.

Liem KF Jr, Jessell TM, Briscoe J. (2000) Regulation of the neural patterning activity of sonic hedgehog by secreted BMP inhibitors expressed by notochord and somites. Development. 127(22):4855-66.

Sander M, Paydar S, Ericson J, Briscoe J, Berber E, German M, Jessell TM, Rubenstein JL. (2000) Ventral neural patterning by Nkx homeobox genes: Nkx6.1 controls somatic motor neuron and ventral interneuron fates. Genes Dev. 14(17):2134-9.

Briscoe J, Pierani A, Jessell TM, Ericson J. (2000) A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube. Cell. 101(4):435-45.

Pasqualetti M, Ori M, Nardi I, Rijli FM. (2000) Ectopic Hoxa2 induction after neural crest migration results in homeosis of jaw elements in Xenopus. Development. 127(24):5367-78.

Fortin G, del Toro ED, Abadie V, Guimaraes L, Foutz AS, Denavit-Saubie M, Rouyer F, Champagnat J. (2000) Genetic and developmental models for the neural control of breathing in vertebrates. Respir Physiol. 122(2-3):247-57. Review.

Poon CS, Zhou Z, Champagnat J. (2000) NMDA receptor activity in utero averts respiratory depression and anomalous long-term depression in newborn mice. J Neurosci. 20(9):RC73.

Abadie V, Champagnat J, Fortin G. (2000) Branchiomotor activities in mouse embryo. Neuroreport. 11(1):141-5.


1999

Stanke M, Junghans D, Geissen M, Goridis C, Ernsberger U, Rohrer H. (1999) The Phox2 homeodomain proteins are sufficient to promote the development of sympathetic neurons. Development. 126(18):4087-94.

Pattyn A, Morin X, Cremer H, Goridis C, Brunet JF. (1999) The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives. Nature. 399(6734):366-70.

Goridis C, Brunet JF. (1999) Transcriptional control of neurotransmitter phenotype. Curr Opin Neurobiol. 9(1):47-53. Review.

Lo L, Morin X, Brunet JF, Anderson DJ. (1999) Specification of neurotransmitter identity by Phox2 proteins in neural crest stem cells. Neuron. 22(4):693-705.

Auclair F, Marchand R, Glover JC. (1999) Regional patterning of reticulospinal and vestibulospinal neurons in the hindbrain of mouse and rat embryos. J Comp Neurol. 411(2):288-300.

Pata I, Studer M, van Doorninck JH, Briscoe J, Kuuse S, Engel JD, Grosveld F, Karis A. (1999) The transcription factor GATA3 is a downstream effector of Hoxb1 specification in rhombomere 4. Development. 126(23):5523-31.

Briscoe J, Ericson J. (1999) The specification of neuronal identity by graded Sonic Hedgehog signalling. Semin Cell Dev Biol. 10(3):353-62. Review.

Briscoe J, Sussel L, Serup P, Hartigan-O'Connor D, Jessell TM, Rubenstein JL, Ericson J. (1999) Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling. Nature. 398(6728):622-7.

Davenne, M., Maconochie, M., Neun, R., Brunet, J-F., Chambon, P., Krumlauf, R. and Rijli, F.M. (1999). Hoxa2 and Hoxb2 control dorsoventral patterns of neuronal development in the rostral hindbrain. Neuron, 22: 677-691.

Fortin, G, Jungbluth, S, Lumsden, A & Champagnat, J (1999) Segmental specification of GABAergic inhibition during development of hindbrain neural networks. Nature Neuroscience 10, 873-877.

Abadie V, Champagnat J, Fortin G, Couly G. (1999) [Sucking-deglutition-respiration and brain stem development genes] Arch Pediatr. 6(10):1043-7. Review. French.

Jacquin TD, Sadoc G, Borday V, Champagnat J. (1999) Pontine and medullary control of the respiratory activity in the trigeminal and facial nerves of the newborn mouse: an in vitro study. Eur J Neurosci. 11(1):213-22.


1998

Fode C, Gradwohl G, Morin X, Dierich A, LeMeur M, Goridis C, Guillemot F. (1998) The bHLH protein NEUROGENIN 2 is a determination factor for epibranchial placode-derived sensory neurons. Neuron. 20(3):483-94.

Hirsch MR, Tiveron MC, Guillemot F, Brunet JF, Goridis C. (1998) Control of noradrenergic differentiation and Phox2a expression by MASH1 in the central and peripheral nervous system. Development. 125(4):599-608.

Yang C, Kim HS, Seo H, Kim CH, Brunet JF, Kim KS. (1998) Paired-like homeodomain proteins, Phox2a and Phox2b, are responsible for noradrenergic cell-specific transcription of the dopamine beta-hydroxylase gene. J Neurochem. 71(5):1813-26.

Kim HS, Seo H, Yang C, Brunet JF, Kim KS. (1998) Noradrenergic-specific transcription of the dopamine beta-hydroxylase gene requires synergy of multiple cis-acting elements including at least two Phox2a-binding sites. J Neurosci. 18(20):8247-60.

Diaz C, Puelles L, Marin F, Glover JC. (1998) The relationship between rhombomeres and vestibular neuron populations as assessed in quail-chicken chimeras. Dev Biol. 202(1):14-28.

Hoover F, Glover JC. (1998) Regional pattern of retinoid X receptor-alpha gene expression in the central nervous system of the chicken embryo and its up-regulation by exposure to 9-cis retinoic acid. J Comp Neurol. 398(4):575-86.

Ericson J, Norlin S, Jessell TM, Edlund T. (1998) Integrated FGF and BMP signaling controls the progression of progenitor cell differentiation and the emergence of pattern in the embryonic anterior pituitary. Development. 125(6):1005-15.

Studer, M., Gavalas, A., Marshall, H., Ariza-McNaughton, L., Rijli, F., Chambon, P. and Krumlauf, R. (1998). Genetic interaction between Hoxa1 and Hoxb1 reveal new roles in regulation of early hindbrain patterning. Development, 125: 1025-1036.

Gavalas, A., Studer, M., Lumsden, A., Rijli, F., Krumlauf, R. and Chambon, P. (1998). Hoxa1 and Hoxb1 synergize in patterning the hindbrain, cranial nerves and second pharyngeal arch. Development, 125: 1123-1136.

Helmbacher F, Pujades C, Desmarquet C, Frain M, Rijli FM, Chambon P, Charnay P. (1998) Hoxa1 and Krox-20 synergize to control the development of rhombomere 3. Development. 125(23):4739-48.

Rijli FM, Gavalas A, Chambon P. (1998) Segmentation and specification in the branchial region of the head: the role of the Hox selector genes. Int J Dev Biol. 42(3 Spec No):393-401. Review.

Vibert JF, Champagnat J, Pakdaman K, Pham J. (1998) Activity in sparsely connected excitatory neural networks: effect of connectivity. Neural Netw. 11(3):415-434.


1997

Pattyn A, Morin X, Cremer H, Goridis C, Brunet JF. (1997) Expression and interactions of the two closely related homeobox genes Phox2a and Phox2b during neurogenesis. Development. 124(20):4065-75.

Morin X, Cremer H, Hirsch MR, Kapur RP, Goridis C, Brunet JF. (1997) Defects in sensory and autonomic ganglia and absence of locus coeruleus in mice deficient for the homeobox gene Phox2a. Neuron.18(3):411-23.]

Ericson J, Briscoe J, Rashbass P, van Heyningen V, Jessell TM. (1997) Graded sonic hedgehog signaling and the specification of cell fate in the ventral neural tube. Cold Spring Harb Symp Quant Biol. 62:451-66.

Ericson J, Rashbass P, Schedl A, Brenner-Morton S, Kawakami A, van Heyningen V, Jessell TM, Briscoe J. (1997) Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling. Cell. 90(1):169-80.

Champagnat J & Fortin, G (1997) Primordial respiratory-like rhythm generation in the vertebrate embryo, Trends in Neurosciences, 20, 119-124

Dupé, V., Davenne, M., Brocard, J., Dollé, P., Mark, M., Dierich, A., Chambon, P., and Rijli, F.M. (1997). In vivo functional analysis of the Hoxa-1 3' retinoic acid response element (3'RARE). Development. 124, 399-410.

Gavalas A, Davenne M, Lumsden A, Chambon P, Rijli FM. (1997) Role of Hoxa-2 in axon pathfinding and rostral hindbrain patterning. Development. 124(19):3693-702.

Mark M, Rijli FM, Chambon P. (1997) Homeobox genes in embryogenesis and pathogenesis.Pediatr Res. 42(4):421-9. Review.

Dupe V, Davenne M, Brocard J, Dolle P, Mark M, Dierich A, Chambon P, Rijli FM. (1997) In vivo functional analysis of the Hoxa-1 3' retinoic acid response element (3'RARE). Development. 124(2):399-410.

Denavit-Saubie M, Champagnat J, Fortin G. (1997) Maturation of brainstem respiratory neuronal networks. Pediatr Pulmonol Suppl. 16:216-7. Review.

Borday V, Kato F, Champagnat J. (1997) A ventral pontine pathway promotes rhythmic activity in the medulla of neonate mice. Neuroreport. 8(17):3679-83.

Jacquin TD, Descoins C, Champagnat J, Denavit-Saubie M. (1997) K+ channels of expiratory neurones in the brain stem preparation of the newborn rat. Neuroreport. 8(17):3673-8.

Borday V, Fortin G, Champagnat J. (1997) Early ontogeny of rhythm generation and control of breathing. Respir Physiol. 110(2-3):245-9. Review.

Champagnat J, Fortin G. (1997) Primordial respiratory-like rhythm generation in the vertebrate embryo.Trends Neurosci. 20(3):119-24. Review.


1996

Tiveron MC, Hirsch MR, Brunet JF. (1996) The expression pattern of the transcription factor Phox2 delineates synaptic pathways of the autonomic nervous system. J Neurosci. 16(23):7649-60.

Diaz C, Glover JC. (1996) Appropriate pattern formation following regulative regeneration in the hindbrain neural tube. Development. 122(10):3095-105.

Glover JC. (1996) Development of second-order vestibular projections in the chicken embryo. Ann N Y Acad Sci. 781:13-20.

Ericson J, Morton S, Kawakami A, Roelink H, Jessell TM. (1996) Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity. Cell. 87(4):661-73.

Taneja R, Thisse B, Rijli FM, Thisse C, Bouillet P, Dolle P, Chambon P. (1996) The expression pattern of the mouse receptor tyrosine kinase gene MDK1 is conserved through evolution and requires Hoxa-2 for rhombomere-specific expression in mouse embryos. Dev Biol. 177(2):397-412.

Jacquin TD, Borday V, Schneider-Maunoury S, Topilko P, Ghilini G, Kato F, Charnay P, Champagnat J. (1996) Reorganization of pontine rhythmogenic neuronal networks in Krox-20 knockout mice. Neuron. 17(4):747-58.

Erickson JT, Conover JC, Borday V, Champagnat J, Barbacid M, Yancopoulos G, Katz DM. (1996) Mice lacking brain-derived neurotrophic factor exhibit visceral sensory neuron losses distinct from mice lacking NT4 and display a severe developmental deficit in control of breathing. J Neurosci. 16(17):5361-71.

Rekling JC, Champagnat J, Denavit-Saubie M. (1996) Thyrotropin-releasing hormone (TRH) depolarizes a subset of inspiratory neurons in the newborn mouse brain stem in vitro. J Neurophysiol. 75(2):811-9.

Rekling JC, Champagnat J, Denavit-Saubie M. (1996) Electroresponsive properties and membrane potential trajectories of three types of inspiratory neurons in the newborn mouse brain stem in vitro. J Neurophysiol. 75(2):795-810.


1990 - 1995

Ericson J, Muhr J, Jessell TM, Edlund T. Sonic hedgehog: a common signal for ventral patterning along the rostrocaudal axis of the neural tube. Int J Dev Biol. 1995 Oct;39(5):809-16. Review.

Ericson J, Muhr J, Placzek M, Lints T, Jessell TM, Edlund T. Sonic hedgehog induces the differentiation of ventral forebrain neurons: a common signal for ventral patterning within the neural tube. Cell. 1995 Jun 2;81(5):747-56.

Ernsberger U, Patzke H, Tissier-Seta JP, Reh T, Goridis C, Rohrer H. The expression of tyrosine hydroxylase and the transcription factors cPhox-2 and Cash-1: evidence for distinct inductive steps in the differentiation of chick sympathetic precursor cells. Mech Dev. 1995 Jul;52(1):125-36.

Groves AK, George KM, Tissier-Seta JP, Engel JD, Brunet JF, Anderson DJ. Differential regulation of transcription factor gene expression and phenotypic markers in developing sympathetic neurons. Development. 1995 Mar;121(3):887-901.

Rijli FM, Matyas R, Pellegrini M, Dierich A, Gruss P, Dolle P, Chambon P. Cryptorchidism and homeotic transformations of spinal nerves and vertebrae in Hoxa-10 mutant mice. Proc Natl Acad Sci U S A. 1995 Aug 29;92(18):8185-9.

Fortin G, Kato F, Lumsden A, Champagnat J. Rhythm generation in the segmented hindbrain of chick embryos.J Physiol. 1995 Aug 1;486 ( Pt 3):735-44.

Bianchi AL, Denavit-Saubie M, Champagnat J. Central control of breathing in mammals: neuronal circuitry, membrane properties, and neurotransmitters. Physiol Rev. 1995 Jan;75(1):1-45. Review.

Glover JC. The organization of vestibulo-ocular and vestibulospinal projections in the chicken embryo. Eur J Morphol. 1994 Aug;32(2-4):193-200.

Fortin G, Champagnat J, Lumsden A. Onset and maturation of branchio-motor activities in the chick hindbrain. Neuroreport. 1994 May 9;5(9):1149-52.

Fortin G, Foutz AS, Champagnat J. Respiratory rhythm generation in chick hindbrain: effects of MK-801 and vagotomy. Neuroreport. 1994 May 9;5(9):1137-40.

Denavit-Saubie M, Kalia M, Pierrefiche O, Schweitzer P, Foutz AS, Champagnat J. Maturation of brain stem neurons involved in respiratory rhythmogenesis: biochemical, bioelectrical and morphological properties.
Biol Neonate. 1994;65(3-4):171-5.

Rijli FM, Mark M, Lakkaraju S, Dierich A, Dolle P, Chambon P. A homeotic transformation is generated in the rostral branchial region of the head by disruption of Hoxa-2, which acts as a selector gene.Cell. 1993 Dec 31;75(7):1333-49.

Tissier-Seta JP, Hirsch MR, Valarche I, Brunet JF, Goridis C. A possible link between cell adhesion receptors, homeodomain proteins and neuronal identity. C R Acad Sci III. 1993 Nov;316(11):1305-15.

Valarche I, Tissier-Seta JP, Hirsch MR, Martinez S, Goridis C, Brunet JF. The mouse homeodomain protein Phox2 regulates Ncam promoter activity in concert with Cux/CDP and is a putative determinant of neurotransmitter phenotype. Development. 1993 Nov;119(3):881-96.

Hemond SG, Glover JC. Clonal patterns of cell proliferation, migration, and dispersal in the brainstem of the chicken embryo. J Neurosci. 1993 Apr;13(4):1387-402.

Glover JC. The development of brain stem projections to the spinal cord in the chicken embryo. Brain Res Bull. 1993;30(3-4):265-71.

Fortin G, Champagnat J. Spontaneous synaptic activities in rat nucleus tractus solitarius neurons in vitro: evidence for re-excitatory processing.
Brain Res. 1993 Dec 10;630(1-2):125-35.

Schweitzer MK, Champagnat J, Denavit-Saubie M. Two distinct phases characterize maturation of neurons in the nucleus of the tractus solitarius during early development: morphological and electrophysiological evidence. J Comp Neurol. 1993 Jan 1;327(1):37-47.

Ericson J, Thor S, Edlund T, Jessell TM, Yamada T. Early stages of motor neuron differentiation revealed by expression of homeobox gene Islet-1. Science. 1992 Jun 12;256(5063):1555-60.

Schweitzer P, Fortin G, Beloeil JC, Champagnat J. In vitro study of newborn rat brain maturation: implication for sudden infant death syndrome. Neurochem Int. 1992 Jan;20(1):109-12.

Morin-Surun MP, Boudinot E, Fournie-Zaluski MC, Champagnat J, Roques BP, Denavit-Saubie M. Control of breathing by endogenous opioid peptides: possible involvement in sudden infant death syndrome.
Neurochem Int. 1992 Jan;20(1):103-7.

Thor S, Ericson J, Brannstrom T, Edlund T. The homeodomain LIM protein Isl-1 is expressed in subsets of neurons and endocrine cells in the adult rat. Neuron. 1991 Dec;7(6):881-9.

Glover JC, Petursdottir G. Regional specificity of developing reticulospinal, vestibulospinal, and vestibulo-ocular projections in the chicken embryo. J Neurobiol. 1991 22:353-76.